Just received my 100-400 last week. I was really on the fence between this and the 180-600 and 150-500. I shoot a good mix of landscape, wildlife, and sports. I ended up going with the 100-400 because I thought it was the most versatile and after taking it out for a race this past weekend I'm very happy with my choice. Excellent IQ and great focal range for many situations. I was also surprised how light and handholdable it was. I shoot with a Lumix 70-200 for work on the S5ii and I was surprised by how much lighter the Z7ii + 100-400 combo felt. I carried it around all day and even ran with it with no issue. Just a superb lens.
NIKON Z 7_2 NIKKOR Z 100-400mm f/4.5-5.6 VR S lens 100mm f/4.5 1/800s 220 ISO -0.7 EV
NIKON Z 7_2 NIKKOR Z 100-400mm f/4.5-5.6 VR S lens 100mm f/4.5 1/800s 64 ISO -0.7 EV
NIKON Z 7_2 NIKKOR Z 100-400mm f/4.5-5.6 VR S lens 100mm f/5.0 1/800s 200 ISO -0.7 EV
NIKON Z 7_2 NIKKOR Z 100-400mm f/4.5-5.6 VR S lens 100mm f/5.0 1/800s 180 ISO -0.7 EV