Steve Spencer Offline Upload & Sell: On
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p.2 #10 · Nikon D6 autofocus - glimpse into Customization options | |
chambeshi wrote:
Off topic to try and discuss epidemiology here, let alone the performance of the WHO, whose performance is exemplary compared against at least two so called developed countries! More pertinently, these myths of this disease being man-made myths etc, is pseudoscience. And this is certainly no place to spread myths about the origins of zoonoses, SARS-CoV19 or other.
I state this as one who has sequenced, analysed and published genomic data (over the past 18 years), and I have also specialized in the evolution and taxonomy of horseshoe bats (Genus Rhinolophus) among other vertebrates. Having read the key peer-reviewed articles published since December (and earlier with respect to SARS-CoV1), the origin is definitely that of a mammalian zoonotic that evolved in a horseshoe bat. It has switched to other hosts at least once before infecting humans (incidentally Ground-zero is not Wuhan). This included hybridization with related strains (possibly Malaysian pangolin).
3 among many pertinent references -
Cheng, V.C., Lau, S.K., Woo, P.C. and Yuen, K.Y., 2007. Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection. Clinical microbiology reviews, 20(4), 660-694.
Lau, S.K., Woo, P.C., Li, K.S., Huang, Y., Tsoi, H.W., Wong, B.H., Wong, S.S., Leung, S.Y., Chan, K.H. and Yuen, K.Y., 2005. Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proceedings of the National Academy of Sciences, 102(39), 14040-14045.
Andersen, K.G., Rambaut, A., Lipkin, W.I., Holmes, E.C. and Garry, R.F., 2020. The proximal origin of SARS-CoV-2. Nature medicine, 26(4), 450-452.
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Thank you for that and sharing your expertise. I apologize for the role I played in the off topic discussion as well.
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