For weight, I think the only semi-modern frame of reference for this lens is the Oly 150-400 f4.5. Obviously different mount and 50mm narrower, however, the weight of the Oly is 4.14lbs. That’s including a built in TC.
If it is truly closer to 4lbs and takes TCs as well as the 300 GM, then I may be tempted to jump on board as well. I miss the Canon 100-500, despite the much darker aperture. The lens was sharp as hell, the AF speed was bananas, and the low weight made handholding for faster BIF shots quite manageable.