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My $0.02 is if you shoot RAW and don't use Capture/ViewNX2 you should disable active D lighting because you can end up with underexposed NEF images.
When ADL is enabled it impacts the camera metering based on the ambient lighting conditions, use of flash, and ADL strength setting. You can demonstrate this to yourself by throwing the camera on a tripod pointing to a particular scene, disabling auto ISO (only so the results of this experiment don't get muddied), put the camera in aperture priority mode and select an appropriate aperture, and disable ADL. Note the shutter speed. Turn on ADL to extra high changing nothing else. You will see the shutter speed get faster for less exposure.
Note the Nikon manual does refer to ADL as "reducing exposure" and this confirms it. It does this to protect highlights. The range of underexposure can range from nothing to about 1 full stop depending on the situation.
When the JPG is created in camera (or when you use NX2), it applies a tone curve that brings up back up shadows more than it does the highlights based on the ADL strength setting which is stored in the exif in a maker note field.
The issue is that Lightroom, Aperture, ACR, etc. don't know about ADL and will ignore the metadata tag in the NEF. So you can end up with underexposed images.
So rather than deal with that risk, it is advisable to disable ADL entirely if you don't use NX2. As I said, that's just my $0.02.