Upload & Sell: Off
Yes, our states have sales taxes from 6 to 10% but (for the moment) they don't have to pay the tax if the product is shipped from another state. So all of our domestic sales, except those to Tennessee, are free of sales tax. This will probably change very soon under the current administration.
No matter which party is in the White House or running (not well) the two houses of Congress this is a likely possibility. The poorer states (like CA, GA, TN, AL, FL, NV, etc.) will jump on it lickety split if they can. They want that revenue stream.
This has been bubbling for quite a while now. All the states with sales taxes want to recover taxes from over-the-border sales because they all need more revenue. Moreover, all the sales tax states already have laws that require people to pay "use taxes" on anything they import over the border anyway--and those laws were in place 'way before Internet sales came into existence. They just haven't found a way to put a finger on Internet sales.
There has been an "Internet lobby" that has so far fought back the issue, but the proponents of "Internet should be free" are actually in the current Administration.