Moocher,
I'm not much for experimentation, although a lot of people are, so my comment may require a pinch of salt.
It's such a fantastic shot of a very cute and expressive little girl that I wonder why you included the red. To me, it's a distraction to that delightful (and slightly mischievious) smile.
Just one person's opinion.
Charlie
Beautiful portrait those eyes are just gorgeous and you captured them so beautifully, but I have to agree with Charlie my eyes are really distracted by the selective coloring here. I would want to focus as much attention as I could to the face,
Love the portrait. The red could be desaturated a bit, or let go grayscale. Frankly, I would have liked the eyes and perhaps a bit on the lips colorized. The shot as is is quite arresting, and the high key look to the comp is very good.