Anyone else noticing drastic color shifts when flattening multiple layers (CS3 on iMac)? I have noticed this when using blend modes of Color, Difference, and others.
Just when I thought I had something, I had to rework the shot...
For accurate viewing of color, you need to look at it at 100% view. Even if you don't, it shouldn't be a drastic change, just very minor. See if that makes a difference.