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I have been doing some testing of my old 35F2, and the results make me think that I would like the new IS version.
When shooting at higher shutter speeds, the outcome is great. I looked through a number of photos where I was happy with portratis. Of course, stopping down helps as well. However, the lens is good wide open, with a clear increase in contrast and resolution at F2.2. Stopped down to F5.6, the lens is super across the frame.
I took a few shots of my daughter at F2, 2.2, and 2.5. The outcome was good at F2, but contrast and color improved at F2.2. The results tell me that the lens will do anything I want in terms of sharp images, as long as I have shutter speed that are high enough. I used bounce flash with M and 1/160 for the test shots on my 60D. I suspect that I just can't hold as steady as I could when I was younger.