The S2 sensor has 56% more area, the usual way to compare sensors (and film), not side length (which is used to compare crops). The S2 sensor is just 7.5% smaller (by area) than the popular 33x44mm chips (P30/P30+/H3D-31/...), and larger than the CFV sensor. No one ever called that one out on not having the MF look. The S2 will certainly look much more similar to MF than to 35mm-FF.
The only versatility the S2 doesn\'t have compared to other systems is that you can\'t remove the back and put it on a technical camera. If you want to do that, don\'t buy an S2. There is also the lack of a wast-level finder, but one of the primary competitors here, the Phase One 645 AF doesn\'t either. The vast majority of MF owners don\'t do this though, so there is a target market there. Furthermore, due to its compact size (smaller than a D3x/1Ds3), relatively fast AF, higher shooting rate, weather sealing, and so on, it adds a lot more flexibility to the equation in other ways, and there are market segments where these will be appreciated very much.