It appears to be very slightly de-centered. But to my eye it also seems not perfectly focused… Even so, it’s pretty marginal here at f4. Try a similar image at 2.8, 4 and 5.6 and really try to nail center focus. Reality for me is if it’s visible at f2.8 — which it often won’t be due to DoF and/or edge falloff, and not visible at f5.6 due to the increased DoF, it probably won’t matter much for most images; and with a frame at f4 you can ascertain whether the amount of its presence is going to be acceptable there for your needs.
Caveat comment few will like, but IMHO with today’s sensors and AF capabilities, it’s really hard for manual focusing to compete. IOW, I suspect many of your manually focused images will be mis-focused by more than the slight amount this lens is de-centered — unless perhaps you’re taking the time to use magnified MF view for every frame…