I have always found that camera RAW files exported as DNG from Topaz DeNoise to Capture One have a pretty serious color cast (casts) making them unusable.
My workflow with C1 is: Process in C1 -Export as Tiff to DeNoise - Export from DeNoise as Tiff.
Playing with the DXO PL4 demo, DXO PL4 seems to have only a minor effect on the color of the DNGs sent to C1.
So C1 users seem to have the option of using DeepPrime as a first step noise reduction plugin and then doing everything else in C1.
DeepPrime seems to do a really good job on noisy DNGs sent to C1.
At first they looked quite blurry in C1 until I realized you have to set noise reduction to zero in C1 after they come from DXO PL4.
Then they sharpened up nicely.
Maybe there are some other catches I found yet though.