I have just recently moved to Nikon and this is my first Nikon zoom, and I have to say I'm very impressed with it. The lens is nice and sharp at every aperture and focal length. At least as good as the Canon 70-200 f/2.8L I used to own. I also like the natural colors it renders.
I will also say that I've used it mostly with the VR turned off and I am still getting nice, crisp shots.
However, if you are using a full frame body like the D3 or the D700, the vignetting at the corners is very noticeable, especially zoomed in. I shoot sports and most of my shots are cropped so this isn't a big deal for me, but in shots you don't crop you will definitely see it.
My only other complaint is a minor annoyance, and that is that the lens hood doesn't seem to hold tight when affixed in the "reverse" position. I've had it fall off on me a couple of times now and I've learned my lesson. I don't reverse it except for storage. If I'm going to be walking any distance with this lens on the body, I make sure the hood in in it's forward position, where it attaches nice and tight.