p.1 #2 · p.1 #2 · Toledo, OH to Savanna, GA (One week)
Cataloochee valley near Maggie Valley NC. Wild Elk heard and some nice historical buildings.
Cades Cove in Tennessee is a treasure trove of nice landscapes and wildlife along with rich historical cabins and buildings. Lot's of black bear and whitetails.
Not sure if you're camping but both of these have campgrounds if you choose to camp. I highly recommend Cades Cove if you've never been there. The road getting into Cataloochee is a tad rough and not for the faint of heart. Both are "out there" and not places you simply swing by on your way through.
p.1 #3 · p.1 #3 · Toledo, OH to Savanna, GA (One week)
In addition to GSMNP, all of western NC has a lot to offer. If you like waterfalls, there are hundreds of them. The area around Greenville, SC also has a lot to see.