Upload & Sell: Off
Seems highly unlikely.
Bridge/ACR and Lightroom never modify camera manufacturer raw files (NEFs, CR2s, etc.). Raw development settings for those files are either kept in a central database or in separate XML files.
The only source files potentially modified by those programs are DNGs, Jpgs, TIFs, and PSDs.
I would suggest looking elsewhere in your workflow and try to exclude potential culprits (camera, memory card, card reader, disk drive, etc.) very carefully, step-by-step.
What can cause confusion sometimes is that raw developers and viewers can be showing you the Jpeg preview that is embedded inside the raw file and that preview may display correctly even if the rest of the raw file is actually corrupt. That can give you the impression that the corruption is occurring later in your work flow than it actually is.
If you see truly convincing evidence that the files are becoming corrupted after being copied to your PC, I would still consider general disk degradation or malware as more likely culprits than Bridge/ACR.