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With my 5D2, I much prefer the 28mm 2.8 IS over my 24-105L for walkaround. The 28mm 2.8 IS is so small and light that it is a pleasure to have around. Makes the 24-105L seem like a beast.
The 28mm also works great for events. Shot a wedding and b-day party with just it. Worked great.
The only time I reach for the 24-105L is oddly enough for portraits (senior, baby.) I guess also for landscapes, but I haven't done much of that recently.