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The D800e file size slows down any workflow, but those files are special. I went from a D3s, to a D800e, to a D4 and noticed a distinctive slow down in my workflow when processing D800e files. I used Phase One Capture One Pro for years, but gave up on it during version 4, which was too unstable. You might give the current version a try, it is faster than Nikon's NX2 or LR, but still not stable on my Mac Pro and has a higher learning curve.