Upload & Sell: Off
If your on a pukka Mac Pro then about the only thing you can do is delete the preferences file, increase the cache size and put the cache on an SSD, fix the noise and sharpening sliders at zero until you have finished al other edits.
Ultimately, 'No' is the short answer. On an iMac, an MBP and a 4.5 Ghz O'clocked hackintosh/windows box with 16GB RAM and a 256 MB SATA 6 SSD, Its still gets laggy on the noise sliders. Once the noise sliders are set, everything gets laggy.
However, those steps above should get you closer to 'happy'.