Upload & Sell: On
I don't know the Dell, so can't say much. I have two Eizo CG241Ws, that using the Eizo ColorNavigator calibration software, hardware calibrates the monitor itself, not the graphic card, so anything that appears on the display is calibrated. I also use the new X-rite i1 Display Pro puck that I find better than anything I've used to date. I find that this all helps clarity over what LR4 is doing, especially the subtleties.
Often I use Auto Tone first to see what it does with an image, then either adjust those settings to my liking, or if I don't like it, reset and mess around with it myself. I don't use the contrast slider much, but playing around between the Clarity and Saturation sliders, approaching contrast with colors differently, and/or may play with Highlights, Whites and Blacks for grey scale contrast or recovery to accent what I want out of the image. I find I have more control in LR4 than in LR3, which somehow felt kinda vague and lurchy.