Upload & Sell: Off
I am far from an expert.
As for the eye of the fly? Do you use noise reduction at all. If so when ticking the "remove jpeg artefacts" can cause smudging big time, if there none to control.
Just one thought of many possibilities.
I think it best if you explained what your process is to get a web size, that is a good starting point.
I crop the image taken by my 12-50mm to 1000 pixels on long side. Tried 'absolute sharpening for web' script or photoshop sharpening tools to sharpen, still loose the detail in the eye which is there in the original image at 100% view. No noise reduction either in the camera or during processing.
Can you please let me know your workflow to web size? Thank you.