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The in camera sensor cleaning isn't all that effective.
On the contrary, there have been several instances where I've had spots on my 7D sensor and running the in-camera sensor cleaning mechanism a few times in a row has solved the problem. When that hasn't worked, a quick cleaning with a rocket blower, as suggested above, has done the job
I haven't had to perform a wet cleaning at all in three years of owning the camera, even though I sometimes remove and/or install an extender while in the field.